Human VCAM1 activation kit by CRISPRa

CAT#: GA105108

VCAM1 CRISPRa kit - CRISPR gene activation of human vascular cell adhesion molecule 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VCAM1
• Locus ID: 7412
• Kit Components:

  GA105108G1, VCAM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105108G2, VCAM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105108G3, VCAM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001078, NM_001199834, NM_080682
• Synonyms: CD106; INCAM-100
• Summary: 'This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]'