Human VDAC1 activation kit by CRISPRa

CAT#: GA105111

VDAC1 CRISPRa kit - CRISPR gene activation of human voltage dependent anion channel 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VDAC1
• Locus ID: 7416
• Kit Components:

  GA105111G1, VDAC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105111G2, VDAC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105111G3, VDAC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003374, NR_036624, NR_036625
• Synonyms: PORIN; VDAC-1
• Summary: 'This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.[provided by RefSeq, Sep 2010]'