Human VDAC2 activation kit by CRISPRa

CAT#: GA105112

VDAC2 CRISPRa kit - CRISPR gene activation of human voltage dependent anion channel 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VDAC2
• Locus ID: 7417
• Kit Components:

  GA105112G1, VDAC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105112G2, VDAC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105112G3, VDAC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001184783, NM_001184823, NM_003375, NR_033675, NM_001324087, NM_001324088, NM_001324089, NM_001324090
• Synonyms: POR
• Summary: 'This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]'