Human Ezrin (EZR) activation kit by CRISPRa

CAT#: GA105121

EZR CRISPRa kit - CRISPR gene activation of human ezrin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EZR
• Locus ID: 7430
• Kit Components:

  GA105121G1, Ezrin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105121G2, Ezrin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105121G3, Ezrin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001111077, NM_003379
• Synonyms: CVIL; CVL; HEL-S-105; VIL2
• Summary: 'The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]'