Human VIP activation kit by CRISPRa

CAT#: GA105123

VIP CRISPRa kit - CRISPR gene activation of human vasoactive intestinal peptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VIP
• Locus ID: 7432
• Kit Components:

  GA105123G1, VIP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105123G2, VIP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105123G3, VIP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003381, NM_194435
• Synonyms: PHM27
• Summary: 'The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014]'