Human VLDL Receptor (VLDLR) activation kit by CRISPRa

CAT#: GA105126

VLDLR CRISPRa kit - CRISPR gene activation of human very low density lipoprotein receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VLDLR
• Locus ID: 7436
• Kit Components:

  GA105126G1, VLDL Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105126G2, VLDL Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105126G3, VLDL Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001018056, NM_003383, NM_001322225, NM_001322226
• Synonyms: CAMRQ1; CARMQ1; CHRMQ1; VLDLRCH
• Summary: 'The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq, Aug 2009]'