Human VRK2 activation kit by CRISPRa

CAT#: GA105131

VRK2 CRISPRa kit - CRISPR gene activation of human VRK serine/threonine kinase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VRK2
• Locus ID: 7444
• Kit Components:

  GA105131G1, VRK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105131G2, VRK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105131G3, VRK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130480, NM_001130481, NM_001130482, NM_001130483, NM_001136027, NM_001288836, NM_001288837, NM_001288838, NM_001288839, NM_006296, NR_036441, NR_049781
• Synonyms: vaccinia-related kinase-2; vaccinia related kinase 2; vaccinia virus B1R-related kinase 2
• Summary: 'This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014]'