Human VILIP1 (VSNL1) activation kit by CRISPRa

CAT#: GA105132

VSNL1 CRISPRa kit - CRISPR gene activation of human visinin like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VSNL1
• Locus ID: 7447
• Kit Components:

  GA105132G1, VILIP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105132G2, VILIP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105132G3, VILIP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003385, NM_001366805, NM_001366806, NM_001366803, NM_001366804
• Synonyms: HLP3; HPCAL3; HUVISL1; VILIP; VILIP-1
• Summary: 'This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]'