Human WIPF1 activation kit by CRISPRa

CAT#: GA105138

WIPF1 CRISPRa kit - CRISPR gene activation of human WAS/WASL interacting protein family member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WIPF1
• Locus ID: 7456
• Kit Components:

  GA105138G1, WIPF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105138G2, WIPF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105138G3, WIPF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001077269, NM_003387
• Synonyms: PRPL-2; WAS2; WASPIP; WIP
• Summary: 'This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]'