Human WEE1 activation kit by CRISPRa

CAT#: GA105143

WEE1 CRISPRa kit - CRISPR gene activation of human WEE1 G2 checkpoint kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WEE1
• Locus ID: 7465
• Kit Components:

  GA105143G1, WEE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105143G2, WEE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105143G3, WEE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001143976, NM_003390
• Synonyms: WEE1A; WEE1hu
• Summary: 'This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008]'