Human WFS1 activation kit by CRISPRa

CAT#: GA105144

WFS1 CRISPRa kit - CRISPR gene activation of human wolframin ER transmembrane glycoprotein

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Frequently bought together (1)
qSTAR qPCR primer pairs against Homo sapiens gene WFS1
    • 200 reactions

USD 120.00

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol WFS1
Locus ID 7466
Kit Components

GA105144G1, WFS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105144G2, WFS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105144G3, WFS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001145853, NM_006005
Synonyms CTRCT41; WFRS; WFS; WFSL
Summary 'This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.