Human WNT11 activation kit by CRISPRa

CAT#: GA105157

WNT11 CRISPRa kit - CRISPR gene activation of human Wnt family member 11

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WNT11
• Locus ID: 7481
• Kit Components:

  GA105157G1, WNT11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105157G2, WNT11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105157G3, WNT11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004626
• Synonyms: HWNT11
• Summary: 'The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome. [provided by RefSeq, Jul 2008]'