Human WNT9B activation kit by CRISPRa

CAT#: GA105160

WNT9B CRISPRa kit - CRISPR gene activation of human Wnt family member 9B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WNT9B
• Locus ID: 7484
• Kit Components:

  GA105160G1, WNT9B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105160G2, WNT9B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105160G3, WNT9B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001320458, NM_003396
• Synonyms: WNT14B; WNT15
• Summary: 'The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]'