Human Xanthine Oxidase (XDH) activation kit by CRISPRa

CAT#: GA105165

XDH CRISPRa kit - CRISPR gene activation of human xanthine dehydrogenase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: XDH
• Locus ID: 7498
• Kit Components:

  GA105165G1, Xanthine Oxidase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105165G2, Xanthine Oxidase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105165G3, Xanthine Oxidase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000379
• Synonyms: XAN1; XO; XOR
• Summary: 'Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014]'