Human 14 3 3 eta (YWHAH) activation kit by CRISPRa

CAT#: GA105184

YWHAH CRISPRa kit - CRISPR gene activation of human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: YWHAH
• Locus ID: 7533
• Kit Components:

  GA105184G1, 14 3 3 eta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105184G2, 14 3 3 eta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105184G3, 14 3 3 eta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003405
• Synonyms: YWHA1
• Summary: 'This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]'