Human ZNF136 activation kit by CRISPRa

CAT#: GA105256

ZNF136 CRISPRa kit - CRISPR gene activation of human zinc finger protein 136

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZNF136
• Locus ID: 7695
• Kit Components:

  GA105256G1, ZNF136 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105256G2, ZNF136 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105256G3, ZNF136 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003437, NM_001348013, NM_001348014
• Synonyms: pHZ-20
• Summary: This gene encodes a zinc finger protein containing a Kruppel-associated box (KRAB) A-box domain at its N-terminus, followed by fourteen contiguous C2H2 zinc finger domains and a degenerate zinc finger. The KRAB A-box showed weak transcriptional repressor activity in a reporter gene assay. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]