Human Plzf (ZBTB16) activation kit by CRISPRa

CAT#: GA105263

ZBTB16 CRISPRa kit - CRISPR gene activation of human zinc finger and BTB domain containing 16

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZBTB16
• Locus ID: 7704
• Kit Components:

  GA105263G1, ZBTB16 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105263G2, ZBTB16 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105263G3, ZBTB16 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001018011, NM_006006, NM_001354750, NM_001354751, NM_001354752
• Synonyms: PLZF; ZNF145
• Summary: This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]