Human ZP2 activation kit by CRISPRa

CAT#: GA105312

ZP2 CRISPRa kit - CRISPR gene activation of human zona pellucida glycoprotein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZP2
• Locus ID: 7783
• Kit Components:

  GA105312G1, ZP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105312G2, ZP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105312G3, ZP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001290104, NM_003460
• Synonyms: Zp-2; ZPA
• Summary: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed of three glycoproteins with various functions during fertilization and preimplantation development. The glycosylated mature peptide is one of the structural components of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. Female mice lacking this gene do not form a stable zona matrix and are sterile. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]