Human PTP4A1 activation kit by CRISPRa

CAT#: GA105320

PTP4A1 CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase 4A1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PTP4A1
• Locus ID: 7803
• Kit Components:

  GA105320G1, PTP4A1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105320G2, PTP4A1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105320G3, PTP4A1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003463
• Synonyms: HH72; PRL-1; PRL1; PTP(CAAX1); PTPCAAX1
• Summary: This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. [provided by RefSeq, Jun 2013]