Human ApoER2 (LRP8) activation kit by CRISPRa
CAT#: GA105321
LRP8 CRISPRa kit - CRISPR gene activation of human LDL receptor related protein 8
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | LRP8 |
Locus ID | 7804 |
Kit Components | GA105321G1, LRP8 gRNA vector 1 in pCas-Guide-CRISPRa GA105321G2, LRP8 gRNA vector 2 in pCas-Guide-CRISPRa GA105321G3, LRP8 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001018054, NM_004631, NM_017522, NM_033300 |
Synonyms | APOER2; HSZ75190; LRP-8; MCI1 |
Summary | This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011] |
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Other Versions
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KN208674 | LRP8 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN208674BN | LRP8 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN208674LP | LRP8 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN208674RB | LRP8 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN408674 | LRP8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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