Human Chromogranin C (SCG2) activation kit by CRISPRa

CAT#: GA105339

SCG2 CRISPRa kit - CRISPR gene activation of human secretogranin II

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SCG2
• Locus ID: 7857
• Kit Components:

  GA105339G1, SCG2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105339G2, SCG2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105339G3, SCG2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003469
• Synonyms: CHGC; EM66; SgII; SN
• Summary: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq, Jul 2008]