Human BAT3 (BAG6) activation kit by CRISPRa

CAT#: GA105355

BAG6 CRISPRa kit - CRISPR gene activation of human BCL2 associated athanogene 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BAG6
• Locus ID: 7917
• Kit Components:

  GA105355G1, BAG6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105355G2, BAG6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105355G3, BAG6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001098534, NM_001199697, NM_001199698, NM_004639, NM_080702, NM_080703
• Synonyms: BAG-6; BAT3; D6S52E; G3
• Summary: This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]