Human NELFE activation kit by CRISPRa

CAT#: GA105362

NELFE CRISPRa kit - CRISPR gene activation of human negative elongation factor complex member E

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NELFE
• Locus ID: 7936
• Kit Components:

  GA105362G1, NELFE gRNA vector 1 in pCas-Guide-CRISPRa

  GA105362G2, NELFE gRNA vector 2 in pCas-Guide-CRISPRa

  GA105362G3, NELFE gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002904
• Synonyms: D6S45; NELF-E; RD; RDBP; RDP
• Summary: The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. [provided by RefSeq, Jul 2008]