Human FZD3 activation kit by CRISPRa

CAT#: GA105370

FZD3 CRISPRa kit - CRISPR gene activation of human frizzled class receptor 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FZD3
• Locus ID: 7976
• Kit Components:

  GA105370G1, FZD3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105370G2, FZD3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105370G3, FZD3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017412, NM_145866
• Synonyms: Fz-3
• Summary: This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010]