Human MTERF (MTERF1) activation kit by CRISPRa

CAT#: GA105371

MTERF1 CRISPRa kit - CRISPR gene activation of human mitochondrial transcription termination factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MTERF1
• Locus ID: 7978
• Kit Components:

  GA105371G1, MTERF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105371G2, MTERF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105371G3, MTERF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301134, NM_001301135, NM_006980
• Synonyms: MTERF
• Summary: This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcription from the mitochondrial genome; this attenuation allows higher levels of expression of 16S ribosomal RNA relative to the tRNA gene downstream. The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding. There is evidence that, for this protein, the zippers participate in intramolecular interactions that establish the three-dimensional structure required for DNA binding. [provided by RefSeq, Jul 2008]