Human SEM1 activation kit by CRISPRa

CAT#: GA105372

SEM1 CRISPRa kit - CRISPR gene activation of human SEM1 26S proteasome complex subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SHFM1
• Locus ID: 7979
• Kit Components:

  GA105372G1, SHFM1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105372G2, SHFM1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105372G3, SHFM1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001201450, NM_001201451, NM_006304, NR_038948, NM_001349698, NM_001349700, NM_001349701, NM_001349702
• Synonyms: DSS1; ECD; SEM1; SHFD1; Shfdg1; SHSF1
• Summary: The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle. [provided by RefSeq, Jul 2008]