Human TFPI2 activation kit by CRISPRa

CAT#: GA105373

TFPI2 CRISPRa kit - CRISPR gene activation of human tissue factor pathway inhibitor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TFPI2
• Locus ID: 7980
• Kit Components:

  GA105373G1, TFPI2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105373G2, TFPI2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105373G3, TFPI2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271003, NM_001271004, NM_006528
• Synonyms: PP5; REF1; TFPI-2
• Summary: This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]