Human ARHGEF5 activation kit by CRISPRa

CAT#: GA105375

ARHGEF5 CRISPRa kit - CRISPR gene activation of human Rho guanine nucleotide exchange factor 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARHGEF5
• Locus ID: 7984
• Kit Components:

  GA105375G1, ARHGEF5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105375G2, ARHGEF5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105375G3, ARHGEF5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001002861, NM_005435
• Synonyms: DKFZp686N1969; GEF5; guanine nucleotide regulatory protein TIM; P60; P60, TIM, GEF5, TIM1, DKFZp686N1969; Rho guanine nucleotide exchange factor (GEF) 5; rho guanine nucleotide exchange factor 5; TIM; TIM1; transforming immortalized mammary oncogene
• Summary: Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008]