Human FRA1 (FOSL1) activation kit by CRISPRa

CAT#: GA105397

FOSL1 CRISPRa kit - CRISPR gene activation of human FOS like 1, AP-1 transcription factor subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FOSL1
• Locus ID: 8061
• Kit Components:

  GA105397G1, FOSL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105397G2, FOSL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105397G3, FOSL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001300844, NM_001300855, NM_001300856, NM_001300857, NM_005438, NR_125339
• Synonyms: FRA; fra-1; FRA1
• Summary: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]