Human ARD1A (NAA10) activation kit by CRISPRa

CAT#: GA105457

NAA10 CRISPRa kit - CRISPR gene activation of human N(alpha)-acetyltransferase 10, NatA catalytic subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NAA10
• Locus ID: 8260
• Kit Components:

  GA105457G1, NAA10 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105457G2, NAA10 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105457G3, NAA10 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256119, NM_001256120, NM_003491
• Synonyms: ARD1; ARD1A; ARD1P; DXS707; MCOPS1; NATD; OGDNS; TE2
• Summary: N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes an N-terminal acetyltransferase that functions as the catalytic subunit of the major amino-terminal acetyltransferase A complex. Mutations in this gene are the cause of Ogden syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]