Human ACOX2 activation kit by CRISPRa

CAT#: GA105477

ACOX2 CRISPRa kit - CRISPR gene activation of human acyl-CoA oxidase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACOX2
• Locus ID: 8309
• Kit Components:

  GA105477G1, ACOX2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105477G2, ACOX2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105477G3, ACOX2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003500
• Synonyms: BCOX; BRCACOX; BRCOX; THCCox
• Summary: The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe cognitive disability, and death in children. [provided by RefSeq, Mar 2009]