Human CDC7 activation kit by CRISPRa

CAT#: GA105483

CDC7 CRISPRa kit - CRISPR gene activation of human cell division cycle 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDC7
• Locus ID: 8317
• Kit Components:

  GA105483G1, CDC7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105483G2, CDC7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105483G3, CDC7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001134419, NM_001134420, NM_003503, N62245
• Synonyms: CDC7L1; HsCDC7; Hsk1; huCDC7
• Summary: This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008]