Human RECK activation kit by CRISPRa

CAT#: GA105568

RECK CRISPRa kit - CRISPR gene activation of human reversion inducing cysteine rich protein with kazal motifs

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RECK
• Locus ID: 8434
• Kit Components:

  GA105568G1, RECK gRNA vector 1 in pCas-Guide-CRISPRa

  GA105568G2, RECK gRNA vector 2 in pCas-Guide-CRISPRa

  GA105568G3, RECK gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001316345, NM_001316346, NM_001316347, NM_001316348, NM_021111
• Synonyms: ST15
• Summary: The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]