Human CAVIN2 activation kit by CRISPRa

CAT#: GA105570

CAVIN2 CRISPRa kit - CRISPR gene activation of human caveolae associated protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SDPR
• Locus ID: 8436
• Kit Components:

  GA105570G1, SDPR gRNA vector 1 in pCas-Guide-CRISPRa

  GA105570G2, SDPR gRNA vector 2 in pCas-Guide-CRISPRa

  GA105570G3, SDPR gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004657
• Synonyms: cavin-2; CAVIN2; PS-p68; SDR
• Summary: This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. [provided by RefSeq, Sep 2009]