Human NSMAF activation kit by CRISPRa

CAT#: GA105573

NSMAF CRISPRa kit - CRISPR gene activation of human neutral sphingomyelinase activation associated factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NSMAF
• Locus ID: 8439
• Kit Components:

  GA105573G1, NSMAF gRNA vector 1 in pCas-Guide-CRISPRa

  GA105573G2, NSMAF gRNA vector 2 in pCas-Guide-CRISPRa

  GA105573G3, NSMAF gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001144772, NM_003580
• Synonyms: FAN; GRAMD5
• Summary: This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]