Human CUL4A activation kit by CRISPRa

CAT#: GA105583

CUL4A CRISPRa kit - CRISPR gene activation of human cullin 4A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CUL4A
• Locus ID: 8451
• Kit Components:

  GA105583G1, CUL4A gRNA vector 1 in pCas-Guide-CRISPRa

  GA105583G2, CUL4A gRNA vector 2 in pCas-Guide-CRISPRa

  GA105583G3, CUL4A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001008895, NM_001278513, NM_001278514, NM_003589, NM_001354938, NM_001354939, NM_001354940, NM_001354941, NM_001354942, NM_001354943, NM_001354944
• Synonyms: cullin 4A; OTTHUMP00000018753; OTTHUMP00000018754
• Summary: CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]). [supplied by OMIM, Oct 2009]