Human IRS4 activation kit by CRISPRa

CAT#: GA105598

IRS4 CRISPRa kit - CRISPR gene activation of human insulin receptor substrate 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IRS4
• Locus ID: 8471
• Kit Components:

  GA105598G1, IRS4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105598G2, IRS4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105598G3, IRS4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003604
• Synonyms: IRS-4; PY160
• Summary: IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.. [provided by RefSeq, Jul 2008]