Human OFD1 activation kit by CRISPRa

CAT#: GA105604

OFD1 CRISPRa kit - CRISPR gene activation of human OFD1 centriole and centriolar satellite protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: OFD1
• Locus ID: 8481
• Kit Components:

  GA105604G1, OFD1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105604G2, OFD1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105604G3, OFD1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003611, NM_001330209, NM_001330210
• Synonyms: 71-7A; CXorf5; JBTS10; RP23; SGBS2
• Summary: This gene is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified; a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome. [provided by RefSeq, Aug 2016]