Human MAP4K3 activation kit by CRISPRa

CAT#: GA105610

MAP4K3 CRISPRa kit - CRISPR gene activation of human mitogen-activated protein kinase kinase kinase kinase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAP4K3
• Locus ID: 8491
• Kit Components:

  GA105610G1, MAP4K3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105610G2, MAP4K3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105610G3, MAP4K3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270425, NM_003618
• Synonyms: GLK; MAPKKKK3; MEKKK 3; MEKKK3; RAB8IPL1
• Summary: This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]