Human PARG activation kit by CRISPRa

CAT#: GA105623

PARG CRISPRa kit - CRISPR gene activation of human poly(ADP-ribose) glycohydrolase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PARG
• Locus ID: 8505
• Kit Components:

  GA105623G1, PARG gRNA vector 1 in pCas-Guide-CRISPRa

  GA105623G2, PARG gRNA vector 2 in pCas-Guide-CRISPRa

  GA105623G3, PARG gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303486, NM_001303487, NM_001303489, NM_001324381, NM_003631, NR_130168, NR_130169, NR_136752, NR_136753, NR_136754, NR_136755, NR_136756
• Synonyms: PARG99
• Summary: Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]