Human DGKZ activation kit by CRISPRa

CAT#: GA105639

DGKZ CRISPRa kit - CRISPR gene activation of human diacylglycerol kinase zeta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DGKZ
• Locus ID: 8525
• Kit Components:

  GA105639G1, DGKZ gRNA vector 1 in pCas-Guide-CRISPRa

  GA105639G2, DGKZ gRNA vector 2 in pCas-Guide-CRISPRa

  GA105639G3, DGKZ gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001105540, NM_001199266, NM_001199267, NM_001199268, NM_003646, NM_201532, NM_201533
• Synonyms: DAGK5; DAGK6; DGK-ZETA; hDGKzeta
• Summary: The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2010]