Human COPS3 activation kit by CRISPRa

CAT#: GA105647

COPS3 CRISPRa kit - CRISPR gene activation of human COP9 signalosome subunit 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: COPS3
• Locus ID: 8533
• Kit Components:

  GA105647G1, COPS3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105647G2, COPS3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105647G3, COPS3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199125, NM_001316354, NM_001316355, NM_001316356, NM_001316357, NM_001316358, NM_003653
• Synonyms: CSN3; SGN3
• Summary: The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]