Human Alkyl DHAP synthase (AGPS) activation kit by CRISPRa

CAT#: GA105654

AGPS CRISPRa kit - CRISPR gene activation of human alkylglycerone phosphate synthase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AGPS
• Locus ID: 8540
• Kit Components:

  GA105654G1, AGPS gRNA vector 1 in pCas-Guide-CRISPRa

  GA105654G2, AGPS gRNA vector 2 in pCas-Guide-CRISPRa

  GA105654G3, AGPS gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003659
• Synonyms: ADAP-S; ADAS; ADHAPS; ADPS; ALDHPSY; RCDP3
• Summary: This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]