Human CDC14B activation kit by CRISPRa

CAT#: GA105667

CDC14B CRISPRa kit - CRISPR gene activation of human cell division cycle 14B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDC14B
• Locus ID: 8555
• Kit Components:

  GA105667G1, CDC14B gRNA vector 1 in pCas-Guide-CRISPRa

  GA105667G2, CDC14B gRNA vector 2 in pCas-Guide-CRISPRa

  GA105667G3, CDC14B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001077181, NM_003671, NM_033331, NM_033332, NM_001351567, NM_001351568, NM_001351569, NM_001351570, NR_147239
• Synonyms: Cdc14B1; Cdc14B2; CDC14B3; hCDC14B
• Summary: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]