Human PRP18 homolog (PRPF18) activation kit by CRISPRa

CAT#: GA105671

PRPF18 CRISPRa kit - CRISPR gene activation of human pre-mRNA processing factor 18

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRPF18
• Locus ID: 8559
• Kit Components:

  GA105671G1, PRPF18 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105671G2, PRPF18 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105671G3, PRPF18 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003675
• Synonyms: hPrp18; PRP18
• Summary: Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008]