Human kynurenine 3 monooxygenase (KMO) activation kit by CRISPRa

CAT#: GA105675

KMO CRISPRa kit - CRISPR gene activation of human kynurenine 3-monooxygenase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KMO
• Locus ID: 8564
• Kit Components:

  GA105675G1, KMO gRNA vector 1 in pCas-Guide-CRISPRa

  GA105675G2, KMO gRNA vector 2 in pCas-Guide-CRISPRa

  GA105675G3, KMO gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003679
• Synonyms: dJ317G22.1
• Summary: This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease. [provided by RefSeq, Oct 2011]