Human PPAP2C (PLPP2) activation kit by CRISPRa

CAT#: GA105701

PLPP2 CRISPRa kit - CRISPR gene activation of human phospholipid phosphatase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLPP2
• Locus ID: 8612
• Kit Components:

  GA105701G1, PLPP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105701G2, PLPP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105701G3, PLPP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003712, NM_177526, NM_177543
• Synonyms: LPP2; PAP-2c; PAP2-g; PPAP2C
• Summary: The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]