Human CAPS1 (CADPS) activation kit by CRISPRa

CAT#: GA105705

CADPS CRISPRa kit - CRISPR gene activation of human calcium dependent secretion activator

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CADPS
• Locus ID: 8618
• Kit Components:

  GA105705G1, CADPS gRNA vector 1 in pCas-Guide-CRISPRa

  GA105705G2, CADPS gRNA vector 2 in pCas-Guide-CRISPRa

  GA105705G3, CADPS gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003716, NM_183393, NM_183394
• Synonyms: CADPS1; CAPS; CAPS1; UNC-31
• Summary: This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008]