Human HSD17B6 activation kit by CRISPRa

CAT#: GA105714

HSD17B6 CRISPRa kit - CRISPR gene activation of human hydroxysteroid 17-beta dehydrogenase 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HSD17B6
• Locus ID: 8630
• Kit Components:

  GA105714G1, HSD17B6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105714G2, HSD17B6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105714G3, HSD17B6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003725
• Synonyms: HSE; RODH; SDR9C6
• Summary: The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. [provided by RefSeq, Aug 2013]