Human EIF4EBP3 activation kit by CRISPRa

CAT#: GA105721

EIF4EBP3 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 4E binding protein 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EIF4EBP3
• Locus ID: 8637
• Kit Components:

  GA105721G1, EIF4EBP3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105721G2, EIF4EBP3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105721G3, EIF4EBP3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003732
• Synonyms: 4E-BP3; 4EBP3
• Summary: This gene encodes a member of the EIF4EBP family, which consists of proteins that bind to eukaryotic translation initiation factor 4E and regulate its assembly into EIF4F, the multi-subunit translation initiation factor that recognizes the mRNA cap structure. Read-through transcription from the neighboring upstream gene (MASK or ANKHD1) generates a transcript (MASK-BP3) that encodes a protein comprised of the MASK protein sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Oct 2010]